HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

[Propofol was useful for intractable convulsion in a patient with tetanus: a case report].

Abstract
An 82-year-old woman with severe tetanus was admitted to our ICU. Anti-convulsive treatment was started by continuous intravenous administration of midazolam followed by thiamylal. On day 15, thiamylal became insufficient to manage the spastic convulsion without frequent intravenous administration of other sedative and muscle relaxants. On day 16, intravenous infusion of propofol was started at the rate of 1 mg.kg-1.h-1. Propofol was more effective than thiamylal to treat convulsion and to stabilize the sympathetic nerve activity. Propofol was also effective to achieve the better general condition in which enteral nutrition could be started. In this case, propofol was apparently more suitable than thiamylal to manage a patient with tetanic convulsion.
AuthorsToshihide Sato, Kazuyuki Masuda, Yoshitaka Jo, Takefumi Akasaka, Asako Amano, Shinya Ogata
JournalMasui. The Japanese journal of anesthesiology (Masui) Vol. 52 Issue 2 Pg. 174-6 (Feb 2003) ISSN: 0021-4892 [Print] Japan
PMID12649877 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Anticonvulsants
  • Propofol
Topics
  • Aged
  • Aged, 80 and over
  • Anticonvulsants (therapeutic use)
  • Female
  • Humans
  • Infusions, Intravenous
  • Propofol (therapeutic use)
  • Seizures (drug therapy, etiology)
  • Tetanus (complications)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: