Abstract | BACKGROUND:
Mediastinitis after open heart operation is an infrequent, but life-threatening complication with a reported incidence rate between 1% and 4%. Hospital mortality is estimated at 10% to 35%. The aim of the present work was to study the systemic inflammatory reaction as judged by complement activation and cytokine and chemokines release in patients with mediastinitis after open heart operation. METHODS: RESULTS: CONCLUSIONS:
|
Authors | Ivar Risnes, Thor Ueland, Pål Aukrust, Runar Lundblad, Svein Tore Baksaas, Tom Eirik Mollnes, Jan L Svennevig |
Journal | The Annals of thoracic surgery
(Ann Thorac Surg)
Vol. 75
Issue 3
Pg. 981-5
(Mar 2003)
ISSN: 0003-4975 [Print] Netherlands |
PMID | 12645727
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Anti-Bacterial Agents
- CXCL12 protein, human
- Chemokine CXCL12
- Chemokines
- Chemokines, CXC
- Complement Membrane Attack Complex
- Cytokines
- Glycoproteins
- Interleukin-6
- Interleukin-8
- SC5b-9 protein complex
- Complement System Proteins
|
Topics |
- Aged
- Anti-Bacterial Agents
- Chemokine CXCL12
- Chemokines
(blood)
- Chemokines, CXC
(blood)
- Complement Activation
(immunology)
- Complement Membrane Attack Complex
- Complement System Proteins
- Coronary Artery Bypass
- Cytokines
(blood)
- Drug Therapy, Combination
(therapeutic use)
- Female
- Glycoproteins
(blood)
- Heart Valve Prosthesis Implantation
- Heart Valves
(surgery)
- Humans
- Interleukin-6
(blood)
- Interleukin-8
(blood)
- Male
- Mediastinitis
(diagnosis, immunology, surgery)
- Middle Aged
- Postoperative Complications
(diagnosis, immunology, surgery)
- Prognosis
- Reoperation
- Staphylococcal Infections
(diagnosis, immunology, surgery)
|