[Hyposensitization with extracts of house dust and mites adsorbed on aluminium-hydroxyde (allpyral) in children with bronchial asthma (author's transl)].

Abstract

Since the year 1971 the authors have treated 39 asthmatic patients with Allpyral house dust vaccins containing Dermatophagoides farinae extract. 16 of these children previously had similar treatment, but without mite extract, and this was changed because of the poor results. Patients allergic only to house dust and mites were selected according to the skin tests. Skin reaction to mite extract did not change even in symptomfree children in contrast to the decrease or disappearance of skin sensitivity to house dust. 23 out of 39 patients had no symptoms or only mild and short wheezing occasionaly in the last 3-6 months of treatment. There were six patients whose symptoms remained unchanged during the treatment. These children were all among the 16 asthmatics who previously had an unsuccessful house dust hyposensitization. So every patient whose treatment was started with the combined house dust-mite Allpyral has imporved, only 5 of the 23 still had yet a few asthmatic attacks.

• Authors: P Osváth, L Endre
• Journal: Monatsschrift fur Kinderheilkunde (Monatsschr Kinderheilkd (1902)) Vol. 124 Issue 3 Pg. 110-3 (Mar 1976) Germany
• Vernacular Title: Densensibilisationsbehandlung von an Asthma bronchiale leidenden Kindern mit einem auch Milbenextrakt enthaltenden, an Aluminiumhydroxyd adsorbierten Hausstaub-Impfstoff (Allpyral)
• PMID: 1264078 (Publication Type: English Abstract, Journal Article)

Chemical References

• Dust
• Vaccines

Topics

• Asthma (diagnosis, therapy)
• Child
• Desensitization, Immunologic (methods)
• Dust
• Humans
• Immunotherapy
• Mites
• Skin Tests
• Vaccines