[Clinical study of amoxicillin used for treatment of infections of the lower urinary tracts (author's transl)].

Abstract

The following results were obtained from treatment of 29 cases of lower urinary tract infections with amoxicillin. 1. Amoxicillin was remarkably effective in 13 cases of acute cystitis, in terms of effect according to dose and bacterial species. 2. The effective rate of amoxicillin in 10 cases of chronic cystitis amounted only to 30% due to complications and resistant bacteria. (The group given 1,500 mg/day was a little higher in the effective rate than the 750 mg/day group.) 3. Amoxicillin was low in effect against infections with Pseudomonas aeruginosa and hardly effective against bacteria resistant to amoxicillin. 4. So far as this study is concerned, amoxicillin produced good clinical results at a half dose of ampicillin, as in the fundamental experiment. 5. Any severe side effect was observed in no case.

• Authors: Y Kubo, T Ono, N Iwamoto, I Yajima
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 29 Issue 1 Pg. 17-21 (Jan 1976) ISSN: 0368-2781 [Print] Japan
• PMID: 1263337 (Publication Type: English Abstract, Journal Article)

Chemical References

• Ampicillin
• Amoxicillin

Topics

• Acute Disease
• Adult
• Aged
• Amoxicillin (therapeutic use)
• Ampicillin (analogs & derivatives)
• Child
• Chronic Disease
• Cystitis (drug therapy)
• Female
• Humans
• Male
• Middle Aged
• Prostatitis (drug therapy)
• Urethritis (drug therapy)
• Urinary Tract Infections (drug therapy)