[Effectiveness of the oral administration of tomicide in experimental infection].

Abstract

Experimental data on the oral administration of Tomicid using different schemes for the protection of white mice from staphylococcal infection are presented. The use of Tomicid, administered in the maximum dose admissible for mice, ensured the protection of up to 2/3 of the total number of mice. A single oral administration of the preparation immediately after infection protected 1/3 of the survived mice from local staphylococcal infection. Good prospects of using Tomicid for the prevention of catarrhal diseases in guinea pigs were established.

• Authors: L P Blinkova, L G Butova, V V Sergeev, S I Elkina, M L Al'tshuler, N G Kalina
• Journal: Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) 2003 Jan-Feb Issue 1 Pg. 74-7 ISSN: 0372-9311 [Print] Russia (Federation)
• Vernacular Title: Otsenka éffectivnosti énteral'nogo primeneniia "tomitsida" pri éksperimental'noĭ infektsii.
• PMID: 12630361 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Anti-Infective Agents
• Bacteriocins
• tomicide

Topics

• Administration, Oral
• Animals
• Anti-Bacterial Agents (therapeutic use)
• Anti-Infective Agents (therapeutic use)
• Bacteriocins
• Disease Models, Animal
• Guinea Pigs
• Mice
• Staphylococcal Infections (drug therapy)