Understanding cancer through proteomics.

Abstract

Proteomics is a rapidly expanding discipline that aims to gain a comprehensive understanding of the expressions, modification, interactions, and regulation of proteins in cells. New high-throughput technologies, such as protein chips and isotope-coded affinity tag peptide labeling, coupled with classic technologies such as two-dimensional gel electrophoresis and mass spectrometry, complement genomic technologies, providing cancer researchers with powerful tools for cancer diagnosis and prognosis and for the identification of targets for therapy.

• Authors: Woonyoung Choi, Sonya W Song, Wei Zhang
• Journal: Technology in cancer research & treatment (Technol Cancer Res Treat) Vol. 1 Issue 4 Pg. 221-30 (Aug 2002) ISSN: 1533-0346 [Print] United States
• PMID: 12625780 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Proteome

Topics

• Electrophoresis, Gel, Two-Dimensional
• Humans
• Lasers
• Mass Spectrometry
• Neoplasms (diagnosis, genetics, metabolism)
• Prognosis
• Protein Array Analysis
• Protein Binding
• Proteome