Abstract | OBJECTIVE: STUDY DESIGN: Retrospective study. SETTING: University hospital. INTERVENTION: PATIENTS: Twenty-five affected ears of patients with unilateral Ménière's Disease were studied. The patients had received confirmed diagnoses Ménière's Disease; thus, the presence of endolymphatic hydrops was suggested. For the control, 22 ears of 11 normal healthy volunteers who had never had vertigo or hearing disturbance were used. MAIN OUTCOME MEASURE: The amplitude of the p13-n23 biphasic wave before and after furosemide administration. RESULTS: The amplitude of the p13-n23 biphasic wave was significantly enlarged in 7 of 18 cases in which it could be detected before diuretic loading. The biphasic waves appeared after diuretic loading in 3 of 7 cases in which it could not be recorded before loading. Thus, the positive ratio of F-VEMP for unilateral Ménière's Disease was considered to be 40% (10 of 25). The ratio was similar to that of the conventional examinations for endolymphatic hydrops such as the glycerol test, furosemide test, and electrocochleogram. CONCLUSION:
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Authors | Toru Seo, Michiko Node, Akiko Yukimasa, Masafumi Sakagami |
Journal | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
(Otol Neurotol)
Vol. 24
Issue 2
Pg. 283-8
(Mar 2003)
ISSN: 1531-7129 [Print] United States |
PMID | 12621345
(Publication Type: Journal Article)
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Chemical References |
- Diuretics
- Furosemide
- Glycerol
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Topics |
- Adult
- Aged
- Audiometry, Evoked Response
- Diuretics
(administration & dosage, therapeutic use)
- Endolymphatic Hydrops
(diagnosis, physiopathology)
- Evoked Potentials
(physiology)
- Female
- Furosemide
(administration & dosage)
- Glycerol
- Humans
- Injections, Intravenous
- Male
- Meniere Disease
(diagnosis, physiopathology)
- Middle Aged
- Muscle, Skeletal
(physiopathology)
- Severity of Illness Index
- Supine Position
- Time Factors
- Vestibule, Labyrinth
(physiopathology)
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