Abstract | OBJECTIVES: STUDY DESIGN: The study presents a case review of a patient with a subglottic laryngeal paraganglioma treated at our institution, with a literature review of the laryngeal neuroendocrine neoplasms. Included is a review of all four neuroendocrine neoplasms, taking a close look at a comparison between laryngeal paragangliomas and atypical carcinoids tumors. All cases of subglottic laryngeal paragangliomas reported in the literature were also compiled and tabulated. METHODS: The patient's record was reviewed for age, symptomatology, workup, and surgical procedures performed. RESULTS: CONCLUSIONS: It is important to differentiate among the four laryngeal neuroendocrine neoplasms, especially between atypical carcinoids and paragangliomas. Each tumor requires different treatments, with the former requiring a more aggressive approach. Paragangliomas must be completely excised to prevent their recurrence, and this approach should be considered a curative treatment. In addition, the immunohistochemical battery is of paramount importance in obtaining the correct pathological diagnosis.
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Authors | Robert Maisel, Derek Schmidt, Stefan Pambuccian |
Journal | The Laryngoscope
(Laryngoscope)
Vol. 113
Issue 3
Pg. 401-5
(Mar 2003)
ISSN: 0023-852X [Print] United States |
PMID | 12616186
(Publication Type: Case Reports, Journal Article, Review)
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Chemical References |
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Topics |
- Aged
- Calcitonin
(metabolism)
- Carcinoma, Neuroendocrine
(metabolism, pathology, surgery)
- Endoscopy
(methods)
- Female
- Humans
- Immunoenzyme Techniques
- Immunohistochemistry
- Keratins
(metabolism)
- Laryngeal Neoplasms
(metabolism, pathology, surgery)
- Paraganglioma
(metabolism, pathology, surgery)
- Tracheal Neoplasms
(metabolism, pathology, surgery)
- Tracheostomy
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