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Azidomorphine: subjective effects and suppression of morphine abstinence.

Abstract
In man, azidomorphine, a new morphine congener, constricted pupils, produced morphine-like subjective effects and euphoria, and suppressed the morphine abstinence syndrome. Azidomorphine was 10 to 50 times as potent as morphine. It is concluded that in man azidomorphine is a typical morphine-like drug.
AuthorsS C Clark, D R Jasinski, J S Pevnick, J D Griffith
JournalClinical pharmacology and therapeutics (Clin Pharmacol Ther) Vol. 19 Issue 3 Pg. 295-9 (Mar 1976) ISSN: 0009-9236 [Print] United States
PMID1261168 (Publication Type: Journal Article)
Chemical References
  • Azides
  • Miotics
  • Morphine Derivatives
  • Placebos
Topics
  • Azides (therapeutic use)
  • Euphoria
  • Humans
  • Miotics
  • Morphine Dependence (physiopathology)
  • Morphine Derivatives (pharmacology, therapeutic use)
  • Placebos
  • Pupil (drug effects)
  • Substance Withdrawal Syndrome (drug therapy)
  • Time Factors

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