[Clinical experience of gelatin-resorcin-formal (GRF) glue for acute empyema with bronchopleural fistula].

Abstract

Gelatin-resorcin-formal (GRF) glue is a new biological adhesive agent with the advantage of sealing efficacy. We report a successful closure of bronchopleural fistula using this agent. A 77-year-old man underwent cavernostomy for lung aspergillosis. After surgery, he developed methicillin-resistant staphylococcus aureus (MRSA)-empyema with bronchopleural fistula. Thoracoplasty and muscular plombage were performed for filling up the cavity and closure of bronchial fistula. But the fistula relapsed 3 days after surgery. GRF glue was injected into the residual cavity, then air-leakage was completely disappeared with tight adhesion of cavity wall. We consider this agent is useful material for the closure of bronchopleural fistula.

• Authors: T Hasumi, S Yamanaka, H Yamanaka, C Endoh, H Suda
• Journal: Kyobu geka. The Japanese journal of thoracic surgery (Kyobu Geka) Vol. 56 Issue 1 Pg. 82-5 (Jan 2003) ISSN: 0021-5252 [Print] Japan
• PMID: 12607257 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Drug Combinations
• Resorcinols
• gelatin-resorcinol-formaldehyde tissue adhesive
• Formaldehyde
• Gelatin

Topics

• Acute Disease
• Aged
• Aspergillosis (surgery)
• Bronchial Fistula (surgery)
• Drug Combinations
• Empyema, Pleural (surgery)
• Formaldehyde
• Gelatin
• Humans
• Lung Diseases, Fungal (surgery)
• Male
• Pleural Diseases (surgery)
• Postoperative Complications (surgery)
• Reoperation
• Resorcinols
• Respiratory Tract Fistula (surgery)
• Thoracoplasty (methods)