Abstract | BACKGROUND: CASE REPORT: A 45-year-old man, with end-stage renal failure and who had received hemodialysis treatment since 1993, presented a several months-history of blisters of the face and the dorsum of the hands. Laboratory analysis showed: hemoglobin 10 g/dl; a moderate hepatic cytolysis; ferritin 195 ng/l. HIV, HBV, HCV serologies were negative. Porphyries analyses showed a porphyria cutanea tarda pattern. The cutaneous histology was non specific; direct immunofluorescence was negative. The patient received deferoxamine (40 mg/kg intravenously every week for 6 weeks) which led to dramatic improvement of the symptoms. DISCUSSION:
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Authors | P Pitche, E Corrin, P Wolkenstein, J Revuz, M Bagot |
Journal | Annales de dermatologie et de venereologie
(Ann Dermatol Venereol)
Vol. 130
Issue 1 Pt 1
Pg. 37-9
(Jan 2003)
ISSN: 0151-9638 [Print] France |
Vernacular Title | Porphyrie cutanée tardive chez l'hémodialysé. Un cas sévère traité efficacement par déféroxamine. |
PMID | 12605155
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
- Iron Chelating Agents
- Deferoxamine
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Topics |
- Deferoxamine
(therapeutic use)
- Humans
- Iron Chelating Agents
(therapeutic use)
- Male
- Middle Aged
- Porphyria Cutanea Tarda
(drug therapy, etiology)
- Remission Induction
- Renal Dialysis
(adverse effects)
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