[Stunning effects in radioiodine therapy of thyroid carcinoma: existence, clinical effects and ways out].

Abstract	In radioiodine therapy for malignant thyroid disease, the pre-therapeutically administered iodine-131-dose can reduce the potential of thyroid or thyroid carcinoma cells to absorb the following therapeutic iodine-131-dose, possibly leading to its failure. This so called stunning effect is controversially discussed in the scientific community. Here we summarize and evaluate publications with regard to the existence and the effects of stunning as well as possible countermeasures.
Authors	W Koch, P Knesewitsch, K Tatsch, K Hahn
Journal	Nuklearmedizin. Nuclear medicine (Nuklearmedizin) Vol. 42 Issue 1 Pg. 10-4 (Feb 2003) ISSN: 0029-5566 [Print] Germany
Vernacular Title	Stunningeffekte bei der Radioiodtherapie des Schilddrüsenkarzinoms: Existenz, klinische Auswirkungen und Auswege.
PMID	12601448 (Publication Type: Journal Article, Review)
Chemical References	Iodine Radioisotopes
Topics	Humans Iodine Radioisotopes (therapeutic use) Radionuclide Imaging Radiotherapy Dosage Thyroid Neoplasms (diagnostic imaging, radiotherapy) Treatment Outcome

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