Abstract | BACKGROUND:
Tumors showing neuroendocrine differentiation arise in a wide range of organs, and metastatic neuroendocrine tumors may be difficult to differentiate from primary tumors. This report describes an unusual case of metastatic breast carcinoma with neuroendocrine differentiation that presented as a solitary thyroid nodule. The diagnosis was made by fine needle aspiration biopsy (FNAB). CASE: CONCLUSION:
Neuroendocrine carcinomas from various sites show similar cytologic features. In this case, a diagnosis of breast carcinoma metastatic to the thyroid was suggested by the clinical history and confirmed by FNAB with immunocytochemistry.
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Authors | Christine K C Loo, Ivan J Burchett |
Journal | Acta cytologica
(Acta Cytol)
2003 Jan-Feb
Vol. 47
Issue 1
Pg. 83-7
ISSN: 0001-5547 [Print] Switzerland |
PMID | 12585036
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Chromogranins
- Receptors, Estrogen
- Receptors, Progesterone
- Phosphopyruvate Hydratase
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Topics |
- Biopsy, Needle
- Bone Neoplasms
(diagnosis, pathology, secondary)
- Breast Neoplasms
(diagnosis, pathology)
- Carcinoma, Ductal, Breast
(diagnosis, pathology, radiotherapy, surgery)
- Carcinoma, Neuroendocrine
(diagnosis, metabolism, pathology)
- Cell Differentiation
- Chromogranins
(metabolism)
- Cytodiagnosis
- Female
- Humans
- Middle Aged
- Phosphopyruvate Hydratase
(metabolism)
- Receptors, Estrogen
(metabolism)
- Receptors, Progesterone
(metabolism)
- Thyroid Neoplasms
(diagnosis, metabolism, pathology, secondary)
- Thyroid Nodule
(pathology)
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