Preoperative transcervical analgesia for laparoscopic sterilization with Filshie clips. A double blind randomized trial.

Abstract

OBJECTIVE:

To evaluate the use of preoperative transcervical analgesia for reducing postoperative pain from laparoscopic sterilization with Filshie clips.

DESIGN:

A double blind, randomized, placebo-controlled trial.

SETTING:

Gynecologic day-care clinic of Vejle Hospital, Vejle, Denmark.

SAMPLE:

Seventy-eight healthy women were attending the public hospital requesting sterilization.

METHODS:

Participants received bupivacaine 0.25% 20 mL or placebo normal saline 20 mL injected into the uterus, though the fallopian tubes and into the pelvis before tubal occlusion with Filshie clips.

MAIN OUTCOME MEASURES:

Post-operative visual analog pain score and request for analgesia were recorded.

RESULTS:

At 30 min after clip application there was a non-significant reduction in pain-score on VAS. However, at 1, 2, 3 and 4 h median pain score on VAS was similar in both groups. Patients request for postoperative analgesia was similar in the two groups.

CONCLUSIONS:

Preoperative transcervical perfusion of the uterus, fallopian tubes and into the pelvis did not reduce postoperative pain or request for analgesics after laparoscopic sterilization with Filshie clips.

• Authors: Tine Schytte, Jens Aage Soerensen, Benedicte Hauge, Bent Andersen
• Journal: Acta obstetricia et gynecologica Scandinavica (Acta Obstet Gynecol Scand) Vol. 82 Issue 1 Pg. 57-60 (Jan 2003) ISSN: 0001-6349 [Print] United States
• PMID: 12580841 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Adjuvants, Anesthesia
• Anesthetics
• Glycopyrrolate
• Bupivacaine
• Propofol

Topics

• Adjuvants, Anesthesia (therapeutic use)
• Adult
• Anesthetics (therapeutic use)
• Bupivacaine (therapeutic use)
• Data Interpretation, Statistical
• Double-Blind Method
• Fallopian Tubes (drug effects)
• Female
• Glycopyrrolate (therapeutic use)
• Humans
• Laparoscopy
• Pain Measurement (methods)
• Pain, Postoperative (drug therapy, prevention & control)
• Preanesthetic Medication
• Propofol (therapeutic use)
• Statistics, Nonparametric
• Sterilization, Tubal (instrumentation, methods)
• Uterus (drug effects)