Abstract | PURPOSE: Subtenon injection of botulinum toxin may produce results similar to intramuscular injection of the medial rectus muscle for the treatment of acute traumatic sixth nerve palsy. This study was designed to evaluate the clinical efficacy of subtenon injection and to compare our results with those in previously published reports. METHODS: During 3 years at a single institution, 13 patients with traumatic sixth nerve palsy of less than 6 months' duration were treated with subtenon injection of botulinum toxin. The deviation angles before and after injection were recorded. A distance esotropia of less than 10 prism diopters (PD) in the primary position or absence of diplopia at 3 months was defined as recovery. RESULTS: Of the 13 patients treated, 11 (84.5%) had unilateral palsy and 2 (15.4%) had bilateral palsy. The average pre-injection deviation was 39.5 PD of esotropia, and the average post-injection deviation was 17.0 PD. Seven patients experienced recovery and regained binocular single vision; the overall recovery rate was 53.8% (unilateral, 63.6%; bilateral, 0%). Six patients did not recover and subsequently underwent strabismus surgery. CONCLUSION:
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Authors | Ling Yuh Kao, An Ning Chao |
Journal | Journal of pediatric ophthalmology and strabismus
(J Pediatr Ophthalmol Strabismus)
2003 Jan-Feb
Vol. 40
Issue 1
Pg. 27-30
ISSN: 0191-3913 [Print] United States |
PMID | 12580268
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Neuromuscular Agents
- Botulinum Toxins, Type A
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Topics |
- Abducens Nerve Diseases
(drug therapy, etiology, physiopathology)
- Abducens Nerve Injury
(drug therapy, etiology, physiopathology)
- Adolescent
- Adult
- Botulinum Toxins, Type A
(therapeutic use)
- Connective Tissue
(drug effects)
- Craniocerebral Trauma
(complications)
- Diplopia
(etiology, physiopathology)
- Esotropia
(etiology, physiopathology)
- Female
- Humans
- Injections
- Male
- Middle Aged
- Neuromuscular Agents
(therapeutic use)
- Oculomotor Muscles
(innervation)
- Treatment Outcome
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