Recurrent isosporiasis over a decade in an immunocompetent host successfully treated with pyrimethamine.

Abstract

Recurrent isosporiasis in an immunocompetent host is reported. The patient suffered from chronic intermittent diarrhea for over a decade. Multiple short-term administrations of trimethoprim-sulfamethoxazole followed by pyrimethamine, or albendazole combined with tinidazole could not control the relapses. However, treatment with pyrimethamine, 25 mg/d for 20 weeks, was successful.

• Authors: Somchai Jongwutiwes, Pichet Sampatanukul, Chaturong Putaporntip
• Journal: Scandinavian journal of infectious diseases (Scand J Infect Dis) Vol. 34 Issue 11 Pg. 859-62 ( 2002) ISSN: 0036-5548 [Print] England
• PMID: 12578164 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Infective Agents
• Antiprotozoal Agents
• Tinidazole
• Trimethoprim, Sulfamethoxazole Drug Combination
• Albendazole
• Pyrimethamine

Topics

• Albendazole (therapeutic use)
• Animals
• Anti-Infective Agents (therapeutic use)
• Antiprotozoal Agents (therapeutic use)
• Chronic Disease
• Drug Administration Schedule
• Humans
• Immunocompetence
• Isospora (isolation & purification)
• Isosporiasis (drug therapy, parasitology, physiopathology)
• Male
• Middle Aged
• Pyrimethamine (therapeutic use)
• Recurrence
• Time Factors
• Tinidazole (therapeutic use)
• Trimethoprim, Sulfamethoxazole Drug Combination (therapeutic use)