Gliofibrous nodule in the cerebello-medullary fissure.

Abstract

An extra-axial nodule in the cerebello-medullary fissure is described, occurring in a 27-year-old-woman. MRI and CT scans revealed the lesion was a non-enhanced round mass, which was associated with mild atrophy of the surrounding cerebellum, but with no perifocal edema. In the surgical observation, the mass was white, elastic and hard, well demarcated and localized in the cerebello-medullary fissure. Histologically, the lesion was composed of astrocytes and collagen-producing fibroblasts with no anaplasia. These findings suggested that the lesion was hamartomatous, but not neoplastic. This type of gliofibrous nodule has not been previously reported.

• Authors: Kazunari Yoshida, Kenji Hiraga, Hisatsugu Ishimori, Makoto Katayama, Takeshi Kawase, Eiji Ikeda, Makio Mukai
• Journal: Neuropathology : official journal of the Japanese Society of Neuropathology (Neuropathology) Vol. 22 Issue 4 Pg. 290-3 (Dec 2002) ISSN: 0919-6544 [Print] Australia
• PMID: 12564769 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Astrocytes (pathology)
• Brain Diseases (diagnostic imaging, metabolism, pathology, surgery)
• Brain Neoplasms (pathology)
• Cerebellum (pathology)
• Diagnosis, Differential
• Female
• Fibroblasts (pathology)
• Hamartoma (diagnostic imaging, metabolism, pathology, surgery)
• Humans
• Immunohistochemistry
• Magnetic Resonance Imaging
• Medulla Oblongata (pathology)
• Tomography, X-Ray Computed