| Abstract | OBJECTIVE: To review the use of the antiepileptic drug gabapentin for the treatment of various types of tremor. DATA SOURCES: A search of biomedical literature was completed through MEDLINE and EMBASE (1993-May 2002) to identify all clinical trials pertaining to the use of gabapentin for the treatment of tremor in humans. DATA SYNTHESIS: Outcome data from the few published studies have varied widely. Patient groups have been small, and conclusions have been based largely on subjective patient and investigator ratings. CONCLUSIONS: A trial of gabapentin is warranted in patients who fail therapy with traditional agents. Improvement should be measured by a patient's perceived functional ability. |
| Authors | Michele A Faulkner, John M Bertoni, Thomas L Lenz
(Affiliation: School of Pharmacy and Allied Health Professions, Creighton University, Omaha, NE 68178-0401, USA. faulkner at creighton.edu)
|
| Journal | The Annals of pharmacotherapy
(Ann Pharmacother)
Vol. 37
Issue 2
Pg. 282-6
(Feb 2003)
ISSN: 1060-0280 United States |
| PMID | 12549962
(Publication Type: Journal Article, Review)
|
| Chemical References |
- Acetic Acids
- Amines
- Cyclohexanecarboxylic Acids
- gamma-Aminobutyric Acid
- gabapentin
|
| Topics |
- Acetic Acids
(therapeutic use)
- Adult
- Aged
- Amines
- Clinical Trials as Topic
- Cyclohexanecarboxylic Acids
- Humans
- Middle Aged
- Parkinson Disease
(drug therapy)
- Treatment Outcome
- Tremor
(classification, drug therapy, etiology)
- gamma-Aminobutyric Acid
|
