Antimicrobial activity of Ca(OH)2 dental cements: an in vitro study.

The effect of five commercial calcium hydroxide root canal medications (XR-SPAD, Calcicur, Hy-cal, Root-cal, Hypo-cal) and two calcium hydroxide mixtures (with water or glycerin) on the growth of (a) three anaerobic bacteria associated with endodontic infections; and (b) saliva bacterial strains was determined using the agar diffusion inhibitory test. Statistically significant zones of bacterial growth inhibition for all the bacteria tested were observed. Calcium hydroxide mixed with glycerin showed the largest zones of bacterial inhibition, whereas Root-cal was the least active. These results underline the necessity to evaluate the antibacterial potential of endodontic medications against the different bacterial strains commonly isolated from infected root canals.
AuthorsJean-Jacques Morrier, Geneviève Benay, Chrystel Hartmann, Odile Barsotti
JournalJournal of endodontics (J Endod) Vol. 29 Issue 1 Pg. 51-4 (Jan 2003) ISSN: 0099-2399 [Print] United States
PMID12540221 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Anti-Infective Agents, Local
  • Dental Cements
  • Drug Combinations
  • Root Canal Filling Materials
  • Calcium Hydroxide
  • Analysis of Variance
  • Anti-Infective Agents, Local (pharmacology)
  • Bacteria, Anaerobic (drug effects)
  • Calcium Hydroxide (pharmacology)
  • Dental Cements (pharmacology)
  • Dental Pulp Cavity (microbiology)
  • Drug Combinations
  • Fusobacterium nucleatum (drug effects)
  • Microbial Sensitivity Tests
  • Porphyromonas gingivalis (drug effects)
  • Prevotella intermedia (drug effects)
  • Root Canal Filling Materials (pharmacology)
  • Saliva (microbiology)

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