Abstract | BACKGROUND: METHODS: Medical records were retrospectively reviewed to identify children and adolescents in the pediatric intensive care unit (PICU) who received UDCA for the treatment of hyperbilirubinemia and cholestasis. RESULTS: CONCLUSIONS: These preliminary data suggest that UDCA is effective in the treatment of cholestasis and hyperbilirubinemia of various etiologies in the PICU patient. Prospective, randomized trials are warranted to further assess the efficacy of this therapy in this patient population.
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Authors | Reggie George, Amy Stevens, John W Berkenbosch, Julie Turpin, Joseph Tobias |
Journal | Southern medical journal
(South Med J)
Vol. 95
Issue 11
Pg. 1276-9
(Nov 2002)
ISSN: 0038-4348 [Print] United States |
PMID | 12539993
(Publication Type: Journal Article)
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Chemical References |
- Cholagogues and Choleretics
- Ursodeoxycholic Acid
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Topics |
- Adolescent
- Child
- Cholagogues and Choleretics
(therapeutic use)
- Cholestasis
(drug therapy)
- Female
- Humans
- Hyperbilirubinemia
(drug therapy)
- Infant
- Intensive Care Units, Pediatric
- Male
- Retrospective Studies
- Treatment Outcome
- Ursodeoxycholic Acid
(therapeutic use)
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