[Effects of different disinfectants on levels of endotoxin in canals of chronic periapical periodontitis].

Abstract

OBJECTIVE:

The objective of this study is to compare effects of formocresol, camphorated phenol and Ya Kan (metronedazole) on endotoxin levels in canals of chronic periapical periodontitis.

METHODS:

A total of 30 patients with chronic periapical periodontitis were selected from outpatients, and 10 cases each were randomly picked out to treat by sealing with formocresol, camphorated phenol and Ya Kan respectively. All patients were both sampled before and after sealing of these disinfectants, and chromogenic substrate method of limulus amebocyte lysate (LAL) test was used to measure levels of endotoxin.

RESULTS:

The effects of Ya Kan, formocresol and camphorated phenol on levels of endotoxin did not showed significant difference.

CONCLUSION:

Some anti-anaerobic bacterial drugs can be used to treat chronic periapical periodontitis.

• Authors: H Tan, T Hu, Y Xu
• Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology (Hua Xi Kou Qiang Yi Xue Za Zhi) Vol. 19 Issue 4 Pg. 222-4 (Aug 2001) ISSN: 1000-1182 [Print] China
• PMID: 12539725 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Anti-Infective Agents, Local
• Drug Combinations
• Endotoxins
• Formocresols
• Phenols
• Root Canal Irrigants
• Metronidazole
• formocresol
• Camphor
• camphorated phenol

Topics

• Anti-Infective Agents, Local (pharmacology)
• Bacteria, Aerobic (drug effects)
• Camphor (pharmacology)
• Chronic Disease
• Drug Combinations
• Endotoxins (analysis)
• Formocresols (pharmacology)
• Humans
• Metronidazole (pharmacology)
• Periapical Periodontitis (drug therapy)
• Phenols (pharmacology)
• Root Canal Irrigants