Abstract | BACKGROUND: OBJECTIVES: SEARCH STRATEGY: MEDLINE, EMBASE, CINAHL, Central and Science Citation Index were searched up to and including June 2002. SELECTION CRITERIA: DATA COLLECTION AND ANALYSIS: Trial inclusion and methodological quality was assessed by two independent reviewers according to predetermined criteria. Results are presented separately for rotator cuff disease, adhesive capsulitis, full thickness rotator cuff tear and mixed diagnoses, and, where possible, combined in meta-analysis. MAIN RESULTS: Twenty-six trials met inclusion criteria. The number, site and dosage of injections varied widely between studies. The number of participants per trial ranged from 20 to 114 (median 52 participants). Methodological quality was variable. For rotator cuff disease, subacromial steroid injection was demonstrated to have a small benefit over placebo in some trials however no benefit of subacromial steroid injection over NSAID was demonstrated based upon the pooled results of three trials. For adhesive capsulitis, two trials suggested a possible early benefit of intra-articular steroid injection over placebo but there was insufficient data for pooling of any of the trials. One trial suggested short-term benefit of intra-articular corticosteroid injection over physiotherapy in the short-term (success at seven weeks RR=1.66 (1.21, 2.28). REVIEWER'S CONCLUSIONS:
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Authors | R Buchbinder, S Green, J M Youd |
Journal | The Cochrane database of systematic reviews
(Cochrane Database Syst Rev)
Issue 1
Pg. CD004016
( 2003)
ISSN: 1469-493X [Electronic] England |
PMID | 12535501
(Publication Type: Journal Article, Meta-Analysis, Review, Systematic Review)
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Chemical References |
- Adrenal Cortex Hormones
- Anti-Inflammatory Agents, Non-Steroidal
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Topics |
- Adrenal Cortex Hormones
(therapeutic use)
- Adult
- Anti-Inflammatory Agents, Non-Steroidal
(therapeutic use)
- Bursitis
(drug therapy)
- Humans
- Injections, Intra-Articular
- Randomized Controlled Trials as Topic
- Rotator Cuff Injuries
- Shoulder Pain
(drug therapy)
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