ELF fields and photooxidation yielding lethal effects on cancer cells.

Abstract

The lethal effect on human cancer cells was studied under three types of treatment: A) an ELF pulsed sinusoidal of 50 Hz electromagnetic field (PEMF) with amplitudes between 10 and 55 mT; B) the field and a cytostatic agent (actinomycin-C); and C) the field, the cytostatic agent, which has a photodynamic effect, and exposure to a halogen lamp. The results show a decreasing vitality of human K-562 and U-937 cancer cells in suspension with each additional treatment. Combination with other parameters as hyperthermia and/or hyperacidity could yield high killing rates by this noninvasive method.

• Authors: Nelly Traitcheva, Plamena Angelova, Maria Radeva, Hermann Berg
• Journal: Bioelectromagnetics (Bioelectromagnetics) Vol. 24 Issue 2 Pg. 148-50 (Feb 2003) ISSN: 0197-8462 [Print] United States
• PMID: 12524682 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright 2003 Wiley-Liss, Inc.

Chemical References

• cactinomycin
• Dactinomycin

Topics

• Apoptosis (drug effects, radiation effects)
• Dactinomycin (analogs & derivatives, pharmacology)
• Electromagnetic Fields
• Humans
• K562 Cells (drug effects, radiation effects)
• Light
• Photochemotherapy (methods)
• U937 Cells (drug effects, radiation effects)