Effect of Maksar on antioxidant system in rats with type IIa alimentary hyperlipoproteinemia.

Abstract

The development of type IIa alimentary hyperlipoproteinemia in rats was accompanied by changes in activity of glutathione-dependent enzymes, exhaustion of the reserves of antioxidant vitamins in the liver and blood, and intensification of lipid peroxidation. The hepatoprotective preparation Maksar obtained from far-eastern plants Maachia amurensis and containing natural biological antioxidants normalized blood lipid composition, corrected liver lipidosis, and improved the antioxidant defense system.

• Authors: V I Yan'kova, T A Gvozdenko, I L Ivanova, S A Fedoreev, N I Kulesh
• Journal: Bulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 134 Issue 3 Pg. 230-2 (Sep 2002) ISSN: 0007-4888 [Print] United States
• PMID: 12511988 (Publication Type: Journal Article)

Chemical References

• Antioxidants
• Flavonoids
• Lipids
• Phenols
• Plant Extracts
• Polymers
• Polyphenols
• maksar
• Glutathione

Topics

• Animals
• Antioxidants (pharmacology)
• Disease Models, Animal
• Flavonoids
• Glutathione (metabolism)
• Hyperlipoproteinemia Type II (metabolism, therapy)
• Lipid Peroxidation
• Lipids (blood)
• Liver (metabolism)
• Male
• Phenols (pharmacology)
• Plant Extracts (chemistry, pharmacology)
• Polymers (pharmacology)
• Polyphenols
• Rats
• Rats, Wistar