[Combined use of killed vaccines and immunomodulator ridostin for urgent prevention of epidemic stomatitis, Aujeszky disease and carnivore plague in experiment].
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| Abstract |
Results of experimental studies of mice and pigs infected with foot-and-mouth disease virus, minks infected with Aujeszky's disease virus, and dogs infected with canine distemper virus are described. In animals with foot-and-mouth disease and Aujeszky's disease, combined treatment with killed vaccine and immunomodulator Ridostin by the scheme of urgent prophylaxis (3 days before infection) caused 75% (foot-and-mouth disease) and 100% (Aujeszky's disease) prevention of animal death and development of generalized infection. The use of Ridostin by the scheme of urgent prophylaxis in a canine distemper infection focus arrested clinical symptoms of the disease in 50% of animals received immunomodulator. Clinical symptoms of canine distemper in the other dogs treated with immunomodulator were manifested in a mild form, and their appearance was delayed to 23-25 days after contact with infected animal.
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| Authors | I F Barinskiĭ, V I Ulasov, V M Kravchenko, A S Toloknov, I A Lycheva, L M Alimbarova, N P Kosiakova |
| Journal | Voprosy virusologii (Vopr Virusol) 2002 Nov-Dec Vol. 47 Issue 6 Pg. 30-2 ISSN: 0507-4088 [Print] Russia (Federation) |
| Vernacular Title | Sochetannoe ispol'zovanie ubitykh vaktsin i immunomoduliatora ridostina dlia ékstrennoĭ profilaktiki iashchura, bolezni Aueski i chumy plotoiadnykh v éksperimente. |
| PMID | 12508681 (Publication Type: English Abstract, Journal Article) |
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