A new synthesis of a potent cancer chemopreventive agent, 13-oxo-15,16-dinorlabda-8(17),11E-dien-19-oic acid from trans-communic acid.

Abstract	The first synthesis of a labdane diterpenoid, (-)-13-oxo-15,16-dinorlabda-8(17),11E-dien-19-oic acid [(-)-1a], isolated from the stem bark of Thuja standishii (GORD.) CARR., from the major component trans-communic acid (3a) is described.
Authors	Takahiro Katoh, Reiko Tanaka, Masatoshi Takeo, Kiyoharu Nishide, Manabu Node
Journal	Chemical & pharmaceutical bulletin (Chem Pharm Bull (Tokyo)) Vol. 50 Issue 12 Pg. 1625-9 (Dec 2002) ISSN: 0009-2363 [Print] Japan
PMID	12499606 (Publication Type: Journal Article)
Chemical References	13-oxo-15,16-dinorlabda-8(17),11E-dien-19-oic acid Anticarcinogenic Agents Diterpenes communic acid
Topics	Anticarcinogenic Agents (chemical synthesis, isolation & purification) Diterpenes (chemical synthesis, chemistry, isolation & purification) Magnetic Resonance Spectroscopy Molecular Structure Plant Bark (chemistry) Thuja (chemistry)

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