Comparative performance of intraocular lenses in eyes with cataract and uveitis.

Abstract

PURPOSE:

To evaluate the postoperative outcomes in uveitic eyes after phacoemulsification and posterior chamber intraocular lens (IOL) implantation.

SETTING:

Multicenter (19) international study.

METHODS:

This prospective randomized comparative interventional case series comprised 140 eyes of 140 patients who had phacoemulsification and implantation of IOLs of various materials: hydrophobic acrylic (n = 48), silicone (n = 44), poly(methyl methacrylate) (PMMA) (n = 26), or heparin-surface-modified PMMA (HSM PMMA) (n = 22). Preoperative and postoperative grading and control of intraocular inflammation were performed. Clinically significant observations, visual outcomes, and the incidence of postoperative complications were recorded.

RESULTS:

At the final follow-up, 64 eyes (46.3%) had a best corrected visual acuity of 20/40 or better, an improvement that was highly significant (P <.0001). One day after surgery, the acrylic group had the lowest inflammation values and the silicone group the highest (P =.02). The acrylic group continued to have the lowest inflammation grade values until the 3-month follow-up. The acrylic and HSM PMMA groups had the lowest incidence of relapses. Posterior capsule opacification developed in 48 eyes (34.2%), with the highest incidence in the silicone group.

CONCLUSIONS:

Phacoemulsification with IOL implantation in selected uveitic eyes was safe and effective. Acrylic IOLs provided a better visual outcome and lower complication rate than IOLs of other materials.

• Authors: Jorge L Alió, Enrique Chipont, David BenEzra, Mohamed A Fakhry, International Ocular Inflammation Society, Study Group of Uveitic Cataract Surgery
• Journal: Journal of cataract and refractive surgery (J Cataract Refract Surg) Vol. 28 Issue 12 Pg. 2096-108 (Dec 2002) ISSN: 0886-3350 [Print] United States
• PMID: 12498843 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Acrylic Resins
• Coated Materials, Biocompatible
• Silicone Elastomers
• Polymethyl Methacrylate

Topics

• Acrylic Resins
• Adult
• Cataract (complications)
• Coated Materials, Biocompatible
• Female
• Humans
• Lens Implantation, Intraocular
• Lenses, Intraocular
• Male
• Phacoemulsification
• Polymethyl Methacrylate
• Postoperative Complications
• Prognosis
• Prospective Studies
• Silicone Elastomers
• Uveitis (complications)
• Visual Acuity