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Mortality and cancer incidence of workers in Finnish road paving companies.

AbstractBACKGROUND:
This study, a component of the International Agency for Research on Cancer (IARC) Multicentric Study on Cancer Risk Among European Asphalt Workers, aimed at identifying major mortality risks among workers in Finnish road paving companies.
METHODS:
The Finnish cohort was comprised of 9,643 men and women from six road paving companies. The mortality of men employed during at least one season (5,676) was followed up from 1964 until end of 1994; an average of 17 years. Standardized mortality ratios (SMR) and relative risks (RR), the latter based on multivariate Poisson regression models were estimated by occupational group and by various metrics of occupational exposures.
RESULTS:
All-cause mortality was elevated (SMR 1.11, 95% confidence interval, CI 1.03-1.20), mainly due to excesses in accidents, poisonings, and violence (1.29; CI 1.12-1.49), and lung cancer (1.38; 1.03-1.81). Workers exposed to bitumen fumes had a slightly elevated mortality from lung cancer (1.16; 0.69-1.83). Multivariate Poisson regression models with 15-year lag period suggested trends by cumulative exposure to coal tar, organic vapors, silica dust, diesel exhaust, and bitumen fume.
CONCLUSIONS:
The elevated mortality from external causes among Finnish building/ground construction workers was probably due to living conditions and related lifestyles. Some evidence was found for a risk of lung cancer due to occupational exposure, but the confirmation of these findings would require a longer follow-up and improved control for confounding.
AuthorsTimo Kauppinen, Pirjo Heikkilä, Timo Partanen, Simo V Virtanen, Eero Pukkala, Pekka Ylöstalo, Igor Burstyn, Gilles Ferro, Paolo Boffetta
JournalAmerican journal of industrial medicine (Am J Ind Med) Vol. 43 Issue 1 Pg. 49-57 (Jan 2003) ISSN: 0271-3586 [Print] United States
PMID12494421 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
CopyrightCopyright 2003 Wiley-Liss, Inc.
Chemical References
  • Hydrocarbons
  • asphalt
Topics
  • Accidental Falls (statistics & numerical data)
  • Adult
  • Cause of Death
  • Female
  • Finland (epidemiology)
  • Humans
  • Hydrocarbons
  • Incidence
  • Inhalation Exposure
  • Male
  • Neoplasms (epidemiology, mortality)
  • Occupational Diseases (epidemiology, mortality)
  • Occupational Exposure
  • Pancreatic Neoplasms (epidemiology, mortality)
  • Poisson Distribution
  • Risk Assessment

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