Abstract | BACKGROUND: METHODS: We were interested in extending our studies as to whether alpha-lipoic acid might improve the symptomatology in BMS and therefore carried out a larger open controlled clinical study on the effects of alpha-lipoic acid on BMS symptomatology. RESULTS: We have examined the effects on 4 groups of 20 patients with BMS of ALA, compared with bethanecol, Biotene and placebo, and found ALA of remarkable benefit with minimal adverse effects. CONCLUSIONS: These results suggest that double-blind randomized controlled multicenter studies of ALA are indicated.
|
Authors | F Femiano |
Journal | Minerva stomatologica
(Minerva Stomatol)
Vol. 51
Issue 9
Pg. 405-9
(Sep 2002)
ISSN: 0026-4970 [Print] Italy |
PMID | 12473978
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
|
Chemical References |
- Biotene
- Drug Combinations
- Mouthwashes
- Neuroprotective Agents
- Bethanechol
- Thioctic Acid
- Glucose Oxidase
- Lactoperoxidase
- Muramidase
- Xylitol
|
Topics |
- Administration, Oral
- Adult
- Aged
- Bethanechol
(therapeutic use)
- Burning Mouth Syndrome
(drug therapy)
- Cohort Studies
- Drug Combinations
- Female
- Glucose Oxidase
(therapeutic use)
- Humans
- Lactoperoxidase
(therapeutic use)
- Male
- Middle Aged
- Mouthwashes
(therapeutic use)
- Muramidase
(therapeutic use)
- Neuroprotective Agents
(therapeutic use)
- Thioctic Acid
(therapeutic use)
- Treatment Outcome
- Xylitol
(therapeutic use)
|