Oral dexketoprofen for pain treatment during diagnostic hysteroscopy in postmenopausal women.

Abstract

OBJECTIVE:

To assess the efficacy of dexketoprofen (DEX) in reducing pain at different stages of the hysteroscopic procedure in comparison with local anaesthesia in menopausal women.

METHODS:

Menopausal patients affected by uterine bleeding submitted to diagnostic hysteroscopy, were randomised to receive either 25 mg DEX tablet (n = 148) or intracervical injection of 5 ml mepivacaine 2% (n = 150). Pain suffered during the procedure itself and 30, 60, 120 min after, was scored on the 11 point Visual Analogic Scale, recorded and analysed.

RESULTS:

No statistical difference were noted during the procedure itself in both groups of treatment. Patients treated with DEX has significantly less postoperative pain.

CONCLUSIONS:

DEX is not superior to mepivacaine in reducing the discomfort of the procedure but does significantly reduce postoperative pain.

• Authors: Francesco Mercorio, Raffaella De Simone, Paola Landi, Anna Sarchianaki, Giovanni Tessitore, Carmine Nappi
• Journal: Maturitas (Maturitas) Vol. 43 Issue 4 Pg. 277-81 (Dec 10 2002) ISSN: 0378-5122 [Print] Ireland
• PMID: 12468136 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
• Copyright: Copyright 2002 Elsevier Science Ireland Ltd.

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Tromethamine
• Ketoprofen
• Mepivacaine
• dexketoprofen trometamol

Topics

• Administration, Oral
• Anti-Inflammatory Agents, Non-Steroidal (administration & dosage, therapeutic use)
• Female
• Humans
• Hysteroscopy
• Injections
• Ketoprofen (administration & dosage, analogs & derivatives, therapeutic use)
• Mepivacaine (administration & dosage, therapeutic use)
• Pain Measurement
• Pain, Postoperative (drug therapy)
• Postmenopause
• Treatment Outcome
• Tromethamine (administration & dosage, analogs & derivatives, therapeutic use)