[Thoughts on current management of severe neonatal hyperbilirubinemia].

Abstract

In recent years, the threat of kernicterus reappeared with the extension of early discharge of newborns. By the same time new knowledge and technologies have improved the management of neonatal hyperbilirubinemia. Early bilirubin measurement helps to identify those newborns who will be at risk of hyperbilirubinemia after discharge. This measurement can be made instantaneously in a non invasive way using a transcutaneous measurement device. Fibreoptic and conventional phototherapies can be modulated according to the nature and the intensity of hyperbilirubinemia. In a near future enzymatic inhibitors such as Sn-mesoporphyrin will be probably available for the treatment of severe hyperbilirubinemia.

• Authors: M Di Maio, S Besnier
• Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie (Arch Pediatr) Vol. 9 Issue 10 Pg. 1083-6 (Oct 2002) ISSN: 0929-693X [Print] France
• Vernacular Title: Réflexions autour de la prise en charge en maternité des ictères sévères.
• PMID: 12462845 (Publication Type: English Abstract, Journal Article)

Chemical References

• Mesoporphyrins
• mesoporphyrin IX

Topics

• Diagnosis, Differential
• Female
• Humans
• Infant, Newborn
• Jaundice, Neonatal (diagnosis, therapy)
• Male
• Mesoporphyrins (therapeutic use)
• Patient Discharge
• Phototherapy
• Risk Factors