[Changes in the level of short-chain volatile fatty acids and their aldehydes in oral air and fluid during inflammation of oral tissues].

Abstract

It is shown that volatile short-chain fatty acids (propionate, butyrate and acetate) of bacterial and tissue origin are important factors of pathogenesis of oral tissue inflammation. A comparative biochemical study using chromato-mass-spectrometry, gas adsorptive and gas-liquid chromatography of oral media in healthy subjects has discovered that in gingivitis and parodontitis these media contain higher concentrations of short-chain fatty acids and lower ones of relevant aldehydes in intensification of the inflammatory process. The ratios of acetate/acetaldehyde, propionate/acrolein, butyrate/butyraldehyde increase considerably with intensification of parodontic inflammation making these values suitable for assessment of inflammation severity.

• Authors: Iu A Petrovich, A I Volozhin, E S Filatova, O L Fomina
• Journal: Patologicheskaia fiziologiia i eksperimental'naia terapiia (Patol Fiziol Eksp Ter) 2002 Jul-Sep Issue 3 Pg. 25-6 ISSN: 0031-2991 [Print] Russia (Federation)
• Vernacular Title: Izmenenie soderzhaniia korotkotsepochechnykh letuchikh zhirnykh kislot i ikh al'degidov v zhidkosti i vozdukhe rta pri vospalenii tkaneĭ rotovoĭ polosti.
• PMID: 12462179 (Publication Type: English Abstract, Journal Article)

Chemical References

• Acetates
• Aldehydes
• Butyrates
• Fatty Acids, Volatile
• Propionates

Topics

• Acetates (analysis, metabolism)
• Adult
• Air (analysis)
• Aldehydes (analysis, metabolism)
• Butyrates (analysis, metabolism)
• Fatty Acids, Volatile (analysis, metabolism)
• Flame Ionization
• Gas Chromatography-Mass Spectrometry
• Gingivitis (metabolism)
• Humans
• Periodontal Diseases (metabolism)
• Propionates (analysis, metabolism)
• Saliva (metabolism)