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The use of some immunomodulators and non-antibiotic drugs in a prophylaxis and treatment of mastitis.

AbstractAntibiotics are widely used in treatment and prophylaxis of mastitis, but their antibacterial and therapeutic efficacy continues to decrease. New methods of prophylaxis of mastitis with the use of vaccines and biological response modifiers are reviewed. Prophylactic activity of staphylococcal vaccines should be investigated in the future because of difficulties in successful treatment of infections caused by these organisms. Vaccination with J5 bacterin (0111:B4) reduced duration of IMI and local signs of clinical coliform-mastitis. Some immunomodulators proved to be effective in treatment of mastitis during lactating period. Promising results were obtained with the use of giseng saponin, herbal gel, herbal extracts, propolis, lysosubtilin, antibacterial proteins, and lysozyme dimer especially.
AuthorsE Malinowski (Affiliation: Department of Pathophysiology of Reproduction and Mammary Gland. National Veterinary Research Institute, PowstaƄców Wikp, 10, 85-090 Bydgoszcz, Poland.)
JournalPolish journal of veterinary sciences (Pol J Vet Sci) Vol. 5 Issue 3 Pg. 197-202 ( 2002) ISSN: 1505-1773 Poland
PMID12448082 (Publication Type: Journal Article, Review)
Chemical References
  • Adjuvants, Immunologic
  • Vaccines
Topics
  • Adjuvants, Immunologic (therapeutic use)
  • Animals
  • Cattle
  • Mastitis, Bovine (drug therapy, immunology, prevention & control)
  • Phytotherapy
  • Plants, Medicinal
  • Vaccines (immunology)