[Early adverse reactions after vaccination against influenza in chronically ill people].

Abstract

The objective was to assess the early adverse reactions after vaccination against influenza with the use of Fluarix vaccine (SmithKline Beecham) in chronically ill people. 1010 people were selected to undergo vaccination. The group included 621 women aged on average 44.2 years and 389 men aged on average 48.2. The vaccination was conducted simultaneously and the period of adverse reactions monitoring lasted 14 days. The vaccination was performed in accordance with recommendations of manufacturer. All the vaccinated people suffered from circulatory system disorders, bone system disorders, mental disorders and endocrinological problems. They were in the period of remission during the vaccination. The observed symptoms were classified into two categories: local and general. The local symptoms included swelling, reddening and pain in the vaccinated area. 67 people (6.6%) reported swelling, 85 (8.4%) reported reddening, 12 people (1.2%) reported pain in the vaccinated area. The general symptoms included headache, bad mood and temperature over 37.5 degrees C. 19 people (1.9%) reported bad mood, 10 people (1%)--headache and 8 people (0.8%) reported temperature over 37.5 degrees C. Coexistence of two or three types of symptoms was present in 15 cases (1.5%). The low percentage of early adverse reactions encourages a wider use of vaccines against influenza in chronically ill people.

• Authors: Andrzej Gałaj, Grzegorz Grześk, Arkadiusz Kuziemski, Leszek Szadujkis-Szadurski, Anna Durmowicz
• Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960) (Wiad Lek) Vol. 55 Issue 7-8 Pg. 366-72 ( 2002) ISSN: 0043-5147 [Print] Poland
• Vernacular Title: Wczesne objawy niepozadane obserwowane po szczepieniu przeciwgrypowym zastosowanym u przewlekle chorych.
• PMID: 12428564 (Publication Type: English Abstract, Journal Article)

Chemical References

• Influenza Vaccines

Topics

• Adult
• Affect
• Aged
• Chronic Disease (epidemiology)
• Erythema (chemically induced)
• Female
• Fever (chemically induced)
• Humans
• Influenza Vaccines (adverse effects, therapeutic use)
• Influenza, Human (epidemiology, prevention & control)
• Male
• Middle Aged
• Pain (chemically induced)
• Poland (epidemiology)
• Time Factors