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Sensitization of trigeminal nociception specific for migraine but not pain of sinusitis.

Abstract
Trigeminal pain processing was studied in 14 patients with unilateral migraine attacks and 14 age- and sex-matched patients with comparable unilateral headache from frontal sinusitis. Using a nociception-specific blink reflex method (nBR), a facilitation of nBR responses predominantly on the headache side was observed in migraine, but not in sinusitis. The facilitation of trigeminal nociception may be specific for migraine rather than a consequence of peripheral pain such as frontal sinusitis.
AuthorsZ Katsarava, G Lehnerdt, B Duda, J Ellrich, H C Diener, H Kaube
JournalNeurology (Neurology) Vol. 59 Issue 9 Pg. 1450-3 (Nov 12 2002) ISSN: 0028-3878 [Print] United States
PMID12427905 (Publication Type: Comparative Study, Journal Article)
Topics
  • Acute Disease
  • Adult
  • Blinking
  • Female
  • Frontal Sinusitis (physiopathology)
  • Humans
  • Male
  • Middle Aged
  • Migraine Disorders (physiopathology)
  • Nociceptors (physiopathology)
  • Reaction Time
  • Trigeminal Nerve (physiopathology)

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