Abstract | BACKGROUND: METHODS: The charts of all patients with cirrhosis who underwent HR or HT for HCC between 1997 and 2000 were analyzed. RESULTS: The cohort included 44 patients who underwent HR compared with 65 with HT. All patients in the HR group had Child's A disease, in contrast to the HT group, which included 23% Child's A and 77% Child's B and C patients. Whereas all HT patients spent at least three nights in the intensive care unit, 41% of the HR group never required critical care. Perioperative mortality was 7% in both groups. Pathologic analysis revealed T1/T2 disease in 43% of the HR group compared with 75% of the HT group. After 36 months of follow-up, there was no significant difference in overall survival (57% vs. 66%) or disease-free survival (36% vs. 66%) between the two groups. CONCLUSIONS: With overall survival and disease-free survival as the main outcomes, the results of HR versus HT are comparable in Child's A patients with HCC. In this patient subset, HR not only is an effective form of therapy, but is also associated with quicker recovery.
|
Authors | Mohsen Shabahang, Dido Franceschi, Noriyo Yamashiki, Raj Reddy, Peter A Pappas, Kuky Aviles, Sonia Flores, Andrea Chaparro, Joseph U Levi, Danny Sleeman, Andreas G Tzakis, Tomoaki Kato, David M Levi, Alan S Livingstone |
Journal | Annals of surgical oncology
(Ann Surg Oncol)
Vol. 9
Issue 9
Pg. 881-6
(Nov 2002)
ISSN: 1068-9265 [Print] United States |
PMID | 12417510
(Publication Type: Comparative Study, Journal Article)
|
Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Hepatocellular
(complications, mortality, surgery)
- Child
- Female
- Hepatectomy
- Humans
- Liver Cirrhosis
(complications)
- Liver Neoplasms
(complications, mortality, surgery)
- Liver Transplantation
- Male
- Middle Aged
- Retrospective Studies
- Survival Analysis
|