Polyarteritis associated with hypopharyngeal carcinoma.

Abstract

A rare case of polyarteritis associated with a solid tumor is presented. A 66-year-old man was referred to our hospital, because of gangrene in the bilateral fingers and toes, right pleural effusion, and an abnormal sensation in the throat. A diagnosis of polyarteritis was made based on pleuritis, digital gangrene and the arteriography findings. He also had a hypopharyngeal carcinoma. After being treated with intermittent intravenous cyclophosphamide, oral corticosteroid, alprostadil and aspirin, the pleural effusion rapidly disappeared, while the digital gangrene gradually improved. For the treatment of hypopharyngeal carcinoma, radiation therapy was initiated and resulted in complete disappearance.

• Authors: Makoto Okada, Kimihiro Suzuki, Toshihiko Hidaka, Tadashi Shinohara, Kunio Takada, Masahiro Nakajima, Takashi Nakanishi, Fumitaka Ohsuzu
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 41 Issue 10 Pg. 892-5 (Oct 2002) ISSN: 0918-2918 [Print] Japan
• PMID: 12413018 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids
• Immunosuppressive Agents
• Cyclophosphamide
• Methylprednisolone

Topics

• Aged
• Angiography
• Carcinoma, Squamous Cell (complications, diagnostic imaging, therapy)
• Combined Modality Therapy
• Cyclophosphamide (therapeutic use)
• Glucocorticoids (therapeutic use)
• Humans
• Hypopharyngeal Neoplasms (complications, diagnostic imaging, therapy)
• Immunosuppressive Agents (therapeutic use)
• Magnetic Resonance Imaging
• Male
• Methylprednisolone (therapeutic use)
• Paraneoplastic Syndromes (diagnostic imaging, etiology, therapy)
• Pleural Effusion (etiology, therapy)
• Polyarteritis Nodosa (diagnostic imaging, etiology, therapy)
• Radiography, Thoracic
• Treatment Outcome