Congenital oligodendroglioma with initial manifestation of jaundice.

Abstract

Neonatal brain tumor is a rare clinical entity. The initial presentation in affected newborn infants is often subtle, nonspecific, and rarely includes focal neurologic signs. We report a 2-day-old male infant with congenital oligodendroglioma with initial manifestations of hyperbilirubinemia. Phototherapy was started immediately after admission. Because of a tense anterior fontanel and irritable crying, head ultrasonography, computed tomography, and magnetic resonance imaging were performed and revealed a heterogenous brain tumor in the left temporoparietal lobe. Craniotomy and tumor evacuation was performed, and WHO grade III anaplastic oligodendroglioma was confirmed by the pathologic studies. The patient was discharged 3 weeks later, and outpatient follow-up examination revealed a normally developed infant at 6 months of age. The cause of jaundice was thought to be secondary to tumor hemorrhage, which was not infrequent in neonatal brain tumor.

• Authors: Wu-Shiun Hsieh, Rey In Lien, Tai Ngar Lui, Chao Ran Wang, Shih Ming Jung
• Journal: Pediatric neurology (Pediatr Neurol) Vol. 27 Issue 3 Pg. 230-3 (Sep 2002) ISSN: 0887-8994 [Print] United States
• PMID: 12393136 (Publication Type: Case Reports, Journal Article)

Topics

• Brain Neoplasms (congenital, diagnosis, pathology, surgery)
• Craniotomy
• Diagnosis, Differential
• Follow-Up Studies
• Humans
• Infant, Newborn
• Jaundice, Neonatal (diagnosis, etiology)
• Magnetic Resonance Imaging
• Male
• Oligodendroglioma (congenital, diagnosis, pathology, surgery)
• Parietal Lobe (pathology, surgery)
• Temporal Lobe (pathology, surgery)
• Tomography, X-Ray Computed