[Phamacological studies on bamboo grass (1). Acute toxicity and anti-inflammatory and antiulcerogenic activities of water-soluble fraction(Folin) extracted from Sasa albomarginata Makino et Shibata].

Abstract

Folin showed no significant toxic effects in mice. The tail pressure test in mice revealed a potent analgesic effect with a hypothermic effect in rats. A significant decrease was also seen in rat dextran or carrageenin edema. There were no inhibitory effects on the formation of granulation tissue in rats. In addition, Folin administration revealed a tendency to a decrease in pylorus-ligated ulcer of the rat by inhibiting the gastric secretion. Some protective effects from aspirin or caffeine-induced gastric ulcers of the pylorus-ligated rats were also obtained in this fraction.

• Authors: M Shibata, Y Yamatake, M Sakamoto, M Kanamori, K Takagi
• Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica (Nihon Yakurigaku Zasshi) Vol. 71 Issue 5 Pg. 481-90 (Jul 1975) ISSN: 0015-5691 [Print] Japan
• PMID: 1238320 (Publication Type: Journal Article)

Chemical References

• Analgesics
• Anti-Inflammatory Agents
• Plant Extracts

Topics

• Analgesics
• Animals
• Anti-Inflammatory Agents
• Body Temperature (drug effects)
• Edema (drug therapy)
• Gastric Juice (metabolism)
• Male
• Mice
• Plant Extracts (pharmacology, therapeutic use, toxicity)
• Rats
• Stomach Ulcer (drug therapy)