[A case of fibrosing mediastinitis manifesting recurrent nerve palsy].

Abstract

A 68 year-old man was referred and admitted to our hospital because of hoarseness due to recurrent nerve palsy and an anterior mediastinal tumor detected on chest CT. Chest CT showed a low-density tumor surrounding the aorta and branching arteries. Chest MRI revealed a low-intensity tumor in both T1- and T2-weighted images. The tumor was adjacent to the heart and aorta in the upper anterior mediastinum. A biopsy was performed under minimally invasive video-assisted thoracic surgery (VATS) and a diagnosis of fibrosing mediastinitis was made histopathologically. Oral prednisolone treatment markedly reduced the tumor and improved not only abnormal laboratory data such as C-reactive protein, but also the hoarseness. We report herein that steroid monotherapy was successful in treating a case of fibrosing mediastinitis manifesting recurrent nerve palsy.

• Authors: Seigo Minami, Mitsuko Asai, Kouta Iwahori, Tomoki Utsumi, Tetsuo Kido, Kiyoshi Komuta
• Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society (Nihon Kokyuki Gakkai Zasshi) Vol. 40 Issue 7 Pg. 583-7 (Jul 2002) ISSN: 1343-3490 [Print] Japan
• PMID: 12382423 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anti-Inflammatory Agents
• Prednisolone

Topics

• Aged
• Anti-Inflammatory Agents (administration & dosage)
• Fibrosis
• Humans
• Male
• Mediastinitis (complications, drug therapy, pathology)
• Prednisolone (administration & dosage)
• Vocal Cord Paralysis (etiology)