[A 3-dimensional presentation of the functional liver unit].

Abstract

The reconstruction of the liver parenchyma of a golden hamster after poisoning with allyl formate is described. Allyl formate primarily destroys the periportal areas and leads, following the microvascularisation of the liver parenchyma, to a necrosis of the hepatocytes progressing towards the terminal hepatic venule. The still intact parenchymal zones can be characterized by the positive PAS reaction. In this study the preterminal and the terminal portal branches as well as zone 3, situated in the vasculatory periphery, were reconstructed. By this method, a three-dimensional presentation of the acinar functional zones was possible for the first time.

• Authors: D Sasse, A Schenk
• Journal: Acta anatomica (Acta Anat (Basel)) Vol. 93 Issue 1 Pg. 78-87 ( 1975) ISSN: 0001-5180 [Print] Switzerland
• Vernacular Title: Räumliche Darstellung der funktionellen Lebereinheit (Azinus)
• PMID: 1237984 (Publication Type: English Abstract, Journal Article)

Chemical References

• Allyl Compounds
• Formates

Topics

• Allyl Compounds (poisoning)
• Animals
• Cricetinae
• Formates (poisoning)
• Liver (anatomy & histology, blood supply, drug effects, pathology)
• Microcirculation
• Models, Structural