Abstract | PURPOSE: METHODS: The adhesion formation and stability of intraperitoneal abdominal hernia repairs with DualMesh (macroporous ePTFE mesh with a microporous component) and PolyesterComposite (the newly developed polyurethane-covered Dacron mesh) were compared in a rat model. Forty rats were randomly divided into two groups; ten animals from each group were killed after 14 days, and the other ten after 90 days. RESULTS: The number and intensity of adhesions were comparable in the PolyesterComposite and PTFE groups. Loose adhesions were seen in 13 animals and appeared only selectively at the fixation sutures. Both PolyesterComposite and PTFE induced the formation of a smooth neoperitoneum on the intraperitoneal surface and showed a complete ingrowing of the prosthesis in the surrounding tissue. There were no significant differences between the prostheses in terms of clinical herniation pressure and hydroxyproline concentration. CONCLUSIONS: PolyesterComposite and PTFE are both suitable prostheses for intrapertoneal implantation, but PolyesterComposite is less expensive, which is an important advantage for clinical use.
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Authors | Jürgen Zieren, Marco Paul, Thomas Osei-Agyemang, Folkert Maecker, Jochen M Müller |
Journal | Surgery today
(Surg Today)
Vol. 32
Issue 10
Pg. 884-6
( 2002)
ISSN: 0941-1291 [Print] Japan |
PMID | 12376785
(Publication Type: Comparative Study, Evaluation Study, Journal Article)
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Chemical References |
- Polyethylene Terephthalates
- Polytetrafluoroethylene
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Topics |
- Animals
- Dental Prosthesis, Implant-Supported
- Hernia, Ventral
(surgery)
- Polyethylene Terephthalates
- Polytetrafluoroethylene
- Prostheses and Implants
- Random Allocation
- Rats
- Rats, Wistar
- Surgical Mesh
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