Abstract |
Lamivudine has previously been found to be effective not only in patients with compensated liver disease due to hepatitis B virus (HBV) but also in those with hepatic decompensation. However, long-term follow-up of patients with hepatic encephalopathy (HE) has not been previously reported. We describe a patient with recurrent HE associated with decompensated liver cirrhosis due to hepatitis B. After the initiation of treatment with lamivudine, manifestation of HE has not been observed for about 2 years and liver function has improved as well. This experience suggests that improved liver function using lamivudine may contribute to prevention from recurrence of HE.
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Authors | Shinichiro Hanada, Ryukichi Kumashiro, Ryohei Kaji, Masaru Harada, Michio Sata |
Journal | International journal of molecular medicine
(Int J Mol Med)
Vol. 10
Issue 5
Pg. 647-8
(Nov 2002)
ISSN: 1107-3756 [Print] Greece |
PMID | 12373309
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antiviral Agents
- Lamivudine
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Topics |
- Antiviral Agents
(therapeutic use)
- Female
- Hepatic Encephalopathy
(prevention & control)
- Hepatitis B
(complications, drug therapy)
- Humans
- Lamivudine
(therapeutic use)
- Liver Cirrhosis
(drug therapy, etiology)
- Middle Aged
- Recurrence
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