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Urticaria to cetirizine.

Abstract
A patient with recurrent idiopathic urticaria reported exacerbations after treatment with cetirizine. Prick test to cetirizine was negative. Double-blind challenge tests with mizolastine, loratadine, fexofenadine, dexchlorpheniramine, ebastine, ketotifen, and placebo were negative, whereas hydroxyzine and its active metabolite, cetirizine, reproduced the urticaria. Identification of uncommon adverse reactions to H1 antihistamines is important, particularly because they may mimic the underlying disease.
AuthorsR Tella, P Gaig, J Bartra, P Garcia-Ortega
JournalJournal of investigational allergology & clinical immunology (J Investig Allergol Clin Immunol) Vol. 12 Issue 2 Pg. 136-7 ( 2002) ISSN: 1018-9068 [Print] Spain
PMID12371532 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Histamine H1 Antagonists, Non-Sedating
  • Cetirizine
Topics
  • Adult
  • Cetirizine (adverse effects)
  • Drug Hypersensitivity (etiology)
  • Female
  • Histamine H1 Antagonists, Non-Sedating (adverse effects)
  • Humans
  • Urticaria (chemically induced)

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