[Oral administration of pectins for prophylaxis and treatment of purulent septic complications in patients with burns].

Abstract

Clinical and laboratory evaluation of pectins application efficacy demonstrated that the patients treated with pectines has lower frequency of bacteriemia, intoxication, infectious complications and lethality. Pectins use per os resulted by acceleration of burns wounds healing and by lower microbial dissemination. Frequency of coagulase-positive staphylococci, streptococci and enterococci isolation was also lower in the treated group of patients when compared to the control group. Feces microbial profile also demonstrated positive trend--normal microflora (bifidobacteria and lactobacilli) enhanced, opportunistic bacteria diminished. Pectins application provided normalization of leucocytes, lymphocytes, B-lymphocytes, immunoglobulins A and G. The results of investigation demonstrated pectins efficacy at the complex treatment regimes of the patients with burns.

• Authors: E B Lazareva, S V Smirnov, V B Khvatov, T G Spiridonova, E E Bitkova, L U Shramko, D D Men'shikov
• Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] (Antibiot Khimioter) Vol. 47 Issue 4 Pg. 16-9 ( 2002) ISSN: 0235-2990 [Print] Russia (Federation)
• Vernacular Title: Peroral'noe primenenie pektinov dlia profilaktiki i lecheniia gnoĭno-septicheskikh oslozhneniĭ u ozhogovykh bol'nykh.
• PMID: 12369139 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Pectins

Topics

• Adult
• Aged
• Antibody Formation (drug effects)
• Burns (complications, mortality)
• Female
• Humans
• Immunity, Cellular (drug effects)
• Male
• Middle Aged
• Pectins (therapeutic use)
• Sepsis (drug therapy, microbiology, mortality, prevention & control)
• Wound Healing (drug effects)