A European cost-effectiveness study has been conducted using published clinical trial data from multinational studies on chronic venous
leg ulcers and
pressure sores. Data relevant to UK chronic
wound management practice have been extracted and are presented here. A total of 15
pressure sore studies involving 519
wounds, and 12
leg ulcer studies involving 843
ulcers were used in a pooled analysis. The study objectives included the calculation of comparative costs in pound sterling for three different treatment protocols for each
wound type. The protocols have been adapted for UK clinical practice in both hospital and community settings and are based on primary dressings and nurse time costs,
wound cleansing and
debridement, the use of fillers, and compression as appropriate. The focus of the study has been the cost-effectiveness comparison (as measured by cost per healed
wound) of two modern dressings - Granuflex(R)
hydrocolloid dressing and
Apligraf(R) skin replacement - and traditional gauze dressings in the treatment of venous
leg ulcers and, in the case of
pressure sores, comparison of Granuflex(R)
Comfeel(R)
hydrocolloid dressings and traditional saline gauze dressings. The choice of dressings studied was dictated by the available published literature. The construction of treatment protocols and assumptions on treatments otherwise missing from published papers has been achieved through the use of an expert panel. Results show Granuflex(R) to be 50% more cost-effective, at 422 pounds per healed
wound, than
Comfeel(R) (643 pounds) and 500% more so than saline gauze (2548 pounds) in the treatment of
pressure sores. Granuflex(R) at 342 pounds was also more cost-effective than gauze (541 pounds) or
Apligraf(R) (6741 pounds) in the treatment of venous
leg ulcers. These data will provide a valuable adjunct to published clinical evidence, offering further information upon which carers can base their choice of
wound dressing.