[Effect of an anabolic steroid (methenolone enanthate) on the intra- and extravasal albumin pool in liver cirrhosis].

Abstract

15 patients with a histologically and/or peritoneoscopically proven cirrhosis of the liver were treated for four weeks with 200 mg metenolonenanthate (Depot-Primobolan) per week. Before and after the treatment the intravascular and extravascular pool and daily turnover of albumin were measured with 125J-albumin. All patients had a well "compensated" cirrhosis. The only significant difference between the values of the cirrhotic patients and those of a control group of patients was a reduction of the albumin turn-over. The anabolic steroid enlarged the turn-over, the effect was the more pronounced the more pronounced the more the turn over was diminished before the treatment.

• Authors: H Knöbel, K Becker
• Journal: Zeitschrift fur Gastroenterologie (Z Gastroenterol) Vol. 13 Issue 6 Pg. 583-7 (Oct 1975) ISSN: 0044-2771 [Print] Germany
• Vernacular Title: Die Wirkung eines anabol wirkenden Steroids (Metenolonönanthat) auf den intra- und extravasalen Albuminpool bei Leberzirrhose
• PMID: 1224752 (Publication Type: English Abstract, Journal Article)

Chemical References

• Serum Albumin
• Serum Albumin, Radio-Iodinated
• Methenolone

Topics

• Adult
• Aged
• Blood Vessels (metabolism)
• Female
• Humans
• Liver Cirrhosis (drug therapy, metabolism)
• Male
• Methenolone (administration & dosage, therapeutic use)
• Middle Aged
• Serum Albumin (metabolism)
• Serum Albumin, Radio-Iodinated
• Time Factors