Abstract |
The purpose of this study was to investigate clinical, economic, and patient-reported outcomes related to topical cyclosporin A for the treatment of dry eye. The medical records of 181 patients with dry eye were reviewed (mean age, 67.6 yr; 72% women) for up to two years (average follow-up, 1.34 yr) before and after treatment with cyclosporin A 0.05% ophthalmic solution administered topically twice daily. Corneal staining, average discomfort scores, and patient satisfaction markedly improved, whereas the number of prescriptions for ancillary medications and dry eye-related visits to the ophthalmologist declined significantly during the treatment period. In a naturalistic clinical setting, topical cyclosporin A therapy improved the signs and symptoms of dry eye disease, resulting in high patient satisfaction, fewer patients with chronic dry eye visiting the ophthalmologist, and less ancillary drug use.
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Authors | Warren D Cross, Luis F Lay Jr, John G Walt, Chris M Kozma |
Journal | Managed care interface
(Manag Care Interface)
Vol. 15
Issue 9
Pg. 44-9
(Sep 2002)
ISSN: 1096-5645 [Print] United States |
PMID | 12244650
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Immunosuppressive Agents
- Cyclosporine
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Topics |
- Administration, Topical
- Aged
- Cyclosporine
(administration & dosage, economics, therapeutic use)
- Dry Eye Syndromes
(drug therapy, economics)
- Female
- Humans
- Immunosuppressive Agents
(administration & dosage, economics, therapeutic use)
- Male
- Middle Aged
- Patient Satisfaction
- United States
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