[Incidence of HBAg in various liver diseases (comparison between radioimmunologic methods and methods of passive hemagglutination)].

Abstract

In order to determine the frequency of HBAg in Campania, the AA. have examined a large number of liver patients accurately selected and subdivided in five classes: acute hepatitis, chronic hepatitis, cirrhosis, hepatocarcinoma, and various liver diseases. They have employed radioimmuno assays (RIA) with human and guinea pig antibodies and techniques of passive haemoagglutination. The percentage of HBAg positive subjects among the various classes of liver diseases determined with these techniques is significantly higher than the one remarked by the AA. in 1972 by electrosineresis on the same population. Both RIA and haemoagglutination supply satisfactory results, although for haemoagglutination one must remember the subjectiveness of the reading.

• Authors: G M Claar, M C Alvaro, A Ascione, G De Bellis, S Sodano, G L Varone
• Journal: Quaderni Sclavo di diagnostica clinica e di laboratorio (Quad Sclavo Diagn) Vol. 11 Issue 2 Pg. 561-6 (Jun 1975) ISSN: 0033-4979 [Print] Italy
• Vernacular Title: Frequenza dell'HBAg in varie epatopatie (confronto tra metodiche radioimmunologiche e metodiche di emoagglutinazione passiva)
• PMID: 1223959 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Hepatitis B Antigens

Topics

• Antibody Formation
• Chronic Disease
• Hemagglutination Tests
• Hepatitis A (immunology)
• Hepatitis B (immunology)
• Hepatitis B Antigens (isolation & purification)
• Humans
• Liver Cirrhosis (immunology)
• Liver Diseases (immunology)
• Liver Neoplasms (immunology)
• Radioimmunoassay