Lymph node disorders and prognostic value of nodal involvement in patients treated for a borderline ovarian tumor: an analysis of a series of 42 lymphadenectomies.

Abstract

BACKGROUND:

The aim of this study is to evaluate the rate and the clinical outcomes of lymph node involvement in patients treated for borderline ovarian tumor (BOT).

STUDY DESIGN:

Forty-two patients were treated for BOT with a procedure that included lymphadenectomy. Twenty-four patients underwent a pelvic lymphadenectomy, 6 a paraaortic lymphadenectomy, and 12 both procedures. Thirty-two patients underwent systematic lymphadenectomy, five because of associated cancer (uterine cervix or corpus) and five because of bulky nodes discovered during the surgical procedure.

RESULTS:

An endosalpingiosis was present in 11 (26%) patients who underwent lymphadenectomy. Eight patients had nodal involvement related to the BOT. All patients with nodal involvement had serous BOT with peritoneal implants. None of the patients with a mucinous tumor had nodal involvement. None of the patients with early-stage disease (without peritoneal disease) had nodal involvement discovered after routine lymphadenectomy. None of the patients with nodal involvement died of borderline tumor. One patient died of a complication of adjuvant therapy (leukemia after chemotherapy).

CONCLUSIONS:

The prognosis of patients with borderline tumors of the ovary and nodal involvement is excellent. Routine lymphadenectomy should not be performed in patients with early-stage disease. This procedure should be carried out in patients with serous tumor and enlarged lymph nodes.

• Authors: Sophie Camatte, Philippe Morice, David Atallah, Patricia Pautier, Catherine Lhommé, Christine Haie-Meder, Pierre Duvillard, Damienne Castaigne
• Journal: Journal of the American College of Surgeons (J Am Coll Surg) Vol. 195 Issue 3 Pg. 332-8 (Sep 2002) ISSN: 1072-7515 [Print] United States
• PMID: 12229940 (Publication Type: Journal Article)

Topics

• Adolescent
• Adult
• Aged
• Carcinoma, Endometrioid (pathology, therapy)
• Combined Modality Therapy
• Cystadenoma, Mucinous (pathology, therapy)
• Cystadenoma, Serous (pathology, therapy)
• Female
• Humans
• Lymph Node Excision
• Lymphatic Metastasis (diagnosis)
• Middle Aged
• Neoplasm Staging
• Neoplasms, Complex and Mixed (pathology, therapy)
• Ovarian Neoplasms (pathology, therapy)
• Prognosis
• Retrospective Studies
• Survival Analysis